Medicinal Chemistry & Chemical Biology, Short talk
MC-022

Microcycle: An Integrated Design-Make-Test-Analyse Platform to Accelerate Drug Discovery

A. N. Marziale1
1Novartis Pharma AG, Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland -

Microcycle is an integrated drug discovery platform which utilizes micro-scale chemistry, automated purification, real-time biological and physicochemical profiling in combination with machine learning driven compound design. This modular technology platform enables rapid access to high quality chemical matter, by integrating existing assay technology we deliver an array of profiling data to drive multi-parameter optimization in every learning cycle. This enhanced compound optimization process is generating knowledge for drug discovery projects in a timeframe never before possible. Our inspiration originates from a desire to enable fast and integrated translation of screening hits, into best in class chemical leads founded on deep collaborations with drug discovery teams.